FOB / Topicalisation

Last modified: 14 September 2023, 10:53:32 AM AEST
Gems1 / 5
  • Lignocaine 10% = 100 mg/mL
    • 1 spray = 100 micromL = 10 mg
    • Allows "sprays/kg"
      • Lignocaine max = 7 mg/kg
      • 70 kg = at 10 mg/kg is 700 mg = 70 sprays of 10%
  • Max dose
    • Serum concentration 5 mcg/mL
    • 15.4 mg/kg may be used without serious adverse effects but subjective symptoms of lidocaine toxicity were reported in studies using 9.6 mg/kg (Level 2+ evidence, BTS 2013)
    • Effective cough suppression achievable with low total doses ~ 160 mg
  • Traditional limits
    • Lidocaine with adrenaline = 7 mg/kg
    • Lidocaine without = 4.5-5 mg/kg
  • Drixine
    • Oxymetazoline
    • Can use this = separate LA from vasoC
  • Coughing means the LA has reached the cords / trachea
  • Definitive endotracheal = carina, not ETCO2 (could be from mouth)
Technique / description2 / 5
  • Glycopyrrolate
    • Dessication
    • Essential for LA to be absorbed by mucous membranes
    • IM is slower and lasts longer
    • Glycopyrrolate 400 mcg IM
  • Other adjuncts
    • Morphine 10 mg IM
    • Metoprolol PO
    • Must have a system that works without a IVC
  • Cophenylcaine spray to nostrils
  • Cophenylcaine cotton bud / ribbon gauze
    • Go below the inferior turbinates
  • Lignocaine 2% gel to nasopharynx
    • This is the same as for IDC insertion
  • Lignocaine 10%
    • Leave until LAST = it will wear off!
    • Spray nasally
    • Then spray orally
  • Epidural catheter
    • 18 G Touhy
    • 2% Lignocaine + Adrenaline 1:200,000
  • Atomiser
    • 14 G IVC
    • 3 way tap

Through the bronchoscope3 / 5
  • O2 tubing + gravity giving set + chooks foot
    • This provides oxygenation, provides excellent LA dispersion, and helps clear secretions also
    • This can be attached to the top of the Ambu also using the supplied connector
  • Syringes direct via connector to top of Ambu
    • Less effective = no airflow, but adequate for vocal cords
  • Epidural catheter
    • Can be less effective, limited by location of holes
LA Syringes4 / 5
  • 1 mL syringes x 10 with 1% lignocaine with Ad
  • 10 mL syringes with 2-3 mL in each with air

References5 / 5

https://www.acecc.org.au/pageBANK/documents/2012%20Airway%20Management%20SIG%20AFOI%20%20Topicalisation%20%20Sedation%20Booklet%20-%20Kirsty%20formatting%20-%20Feb%2020%202019.pdf

British Thoracic Society guideline for diagnostic flexible bronchoscopy in adults: accredited by NICE, 2013