Free Flap Surgery

Last modified: 10 February 2022, 5:33:46 PM AEDT
Gems1 / 6
  • Priority = flap survival
  • Breast reconstruction
    • Implant-based
    • Autologous flap
  • Flap perfusion
    • Q = (π x ΔP x r4) / (8 x μ x L)
    • r = vessel radius
    • L = length
    • μ = blood viscosity
Contraindications2 / 6
  • Hypercoagulable states = ⬆risk anastomotic thrombosis
    • sickle cell anaemia
    • polycythaemia
Technique / description3 / 6
  • Gold standard = deep inferior epigastric perforator free flap
  • Types
    • Pedicled
      • Latissimus dorsi
    • Free flap
      • requires microsurgery
      • harvest ellipse of lower abdominal tissue and transfer to chest
      • TRAM = transverse rectus abdominis myocutaneous
      • DIEP = deep inferior epigastric perforator
        • spares rectus abdominis M = preserves abdominal strength, ⬇risk hernia
  • Microvascular anastomosis to internal mammary A and V in chest
  • Insetting of flap and shaping of transferred tissue
Complications4 / 6
  • Primary ischaemia
    • during flap transfer
    • anaerobic cellular metabolism
    • proportional to duration of ischaemia
    • TRAM flaps (which contain M) are more sensitive to ischaemia
  • Reperfusion
    • begins with vessel declamping after completion of microvascular anastomosis
  • Flap perfusion
    • denervated = loses intrinsic E tone
    • feeding A/V still response to physical (temperature), circulating catecholamines, drugs
    • priorities = avoidance of
      • hypovolaemia
      • hypothermia
      • vasoconstriction
  • Interstitial oedema
    • absence of intact lymphatics
  • Flap failure
    • incidence DIEP = 0.9%

Anaesthetic considerations5 / 6
  • Pre-op

  • Appropriate patient selection is predictor of good clinical outcome in microsurgery

    • Advanced age
    • co-morbidities
    • Smoking = 4 weeks cessation
    • Obesity = Weight loss
  • Intra-op

  • Optimise flap perfusion

    • C = Provision of full, hyperdynamic circulation
      • normovolaemia
      • caution fluid overload
      • internal mammary A = close to heart = excellent perfusion pressure
    • C = maintain MAP
      • ephedrine / phenylephrine appears safe
    • E = Maintain normal body temperature
      • Underbody warming
      • adequate ambient temperature
    • C = adequate Hct
      • optimal balance between viscosity, BQ, adequate O2-carrying capacity = 30-35%
      • careful haemodilution / normovolaemia
    • F = careful fluid management
      • goal-directed therapy
    • H = DVT prophylaxis
      • TEDS + calf compressors
  • Long surgery > 8 hr

    • D = VA (Des / Sevo / Iso)
      • Sevo = may attenuate ischaemic-reperfusion injury
      • Iso = maintains microcirculatory flow
      • TIVA = emergence can be prolonged
    • D = Remifentanil
      • excellent intraop analgesia
      • rapid control of arterial BP
      • marked vasoD
      • negates use of NMBA
    • D = Careful positioning
  • Emergence

  • reduce coughing = ⬆venous pressure, ⬇flap blow

  • techniques

    • remifentanil
    • deep extubation
    • exchange ETT for LMA
  • Post-op


References6 / 6

Anaesthesia for free flap breast reconstruction, BJAE 2016